In 2001, the Japanese motorcycle manufacturer launched the CBR600F4i, an upgraded version of the F4 model that featured numerous changes in the engine, chassis, and bodywork departments.
The bike featured a new subframe that raised the seat by five mm, which allowed more storage room and improved two-up capabilities.
The taillight was smaller with a dual-bulb configuration, the new dash layout featured a large tachometer, and the New LCD included a speedometer, odometer, clock, engine temperature gauge, amber shift light, and trip meters.
The largest change besides the styling was the high-pressure 50 psi Programmed Fuel Injection (PGM-FI) system, which was highlighted by the suffix "i" in the name that allowed more precise response and power delivery over a wider rpm range while reducing emissions.
In 2001 and 2002, due to Honda's association with MotoGP champion Valentino Rossi and its 500th motorcycle Grand Prix victory, the CBR600F4i was also made available in Europe and Australia in two Rossi Replica versions.
The bike's bodywork featured a more racy look and offered a 3% reduction in drag force, while the front cowl housed a new dual headlight that used brighter H7 bulbs instead of the earlier H4 bulbs.
As for the power figures, the 2001 Honda CBR600F4i had its soul brought to life by a 599cc four-stroke four-cylinder liquid-cooled engine that delivered an output power of 110 hp with maximum strength at 12,500 rpm and 65 Nm (48 lb-ft) of torque available at 10,500 rpm.