The F in 2010 MY YZ250F's name indicates we're dealing with the 4-stroke version of the quarter-liter engine. Basically, the upgraded frame and suspensions of the YZ250 have been mated to a new engine. The looks of the YZ250F have been upgraded, with more aggressive graphics, while the engine also received a massive update, with many new components and revised ones, all contributing to more power at the rider's fingertips.
The 5-speed transmission was also upgraded, together with the ignition, radiators, headers, frame and all. The 2010 MY YZ250F is all-new, just like the performance is higher.